Sorry, I should have posted this weeks ago to save others some time.
If you are running openconnect-sso to connect to a Cisco anyconnect VPN, then when you upgrade to Ubuntu Jammy, openssl 3.0 may stop openconnect from working. The easiest way to work around this is to use a custom configuration file as follows:
cat > $HOME/ssl.cnf
openssl_conf = openssl_init
[openssl_init]
ssl_conf = ssl_sect
[ssl_sect]
system_default = system_default_sect
[system_default_sect]
Options = UnsafeLegacyRenegotiation
EOF
Then use this configuration file (only) when running openconnect:
OPENSSL_CONF=~/ssl.cnf openconnect-sso --server=your-server.whatever.com